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CDK12-IN-4 bic acid 2-phosphate 5-dimethoxyphenyl)-3-{[(2S

SKU: 51614732910

4.4
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Description

5-dimethoxyphenyl)-3-{[(2S

and the subsequent increase in the production of vascular endothelial NO

Volume 160

Alvelestat is a bioactive chemical

29)/b13-6+

CDK12-IN-4 bic acid 2-phosphate 5-dimethoxyphenyl)-3-{[(2SCDK12 IN 4, a pyrazolotriazine, is a potent CDK12 inhibitor with an IC50 of 0. 641 M at high ATP (2 mM). CDK12 IN 4 has no effect on CDK2 Cyclin E (IC50>20 M) and CDK9 Cyclin T1 (IC50>20 M) at high ATP (2 mM) (WO2021116178A1). Product information CAS Number: 2651196 69 7 Molecular Weight: 426. 42 Formula: C20H20F2N8O Chemical Name: 8 cyclopropyl N ((6, 7 difluoro 1H benzo[d]imidazol 2 yl)methyl) 2 morpholinopyrazolo[1, 5 a][1, 3, 5]triazin 4 amine

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