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Mcgaraughty S
Diosgenin palmitate
(2007) Mol Cancer Ther
Tubulin inhibitor 6
Chemical Name: methyl (5-(thiophene-2-carbonyl)-1H-benzo[d]imidazol-2-yl)carbamate
CM-272 Catalog No.:M12375-10 Mcgaraughty SCM 272 is a first in class, potent, selective, substrate competitive and reversible dual G9a DNA methyltransferases (DNMTs) inhibitor. CM 272 inhibits G9a, DNMT1, DNMT3A, DNMT3B and GLP with IC50s of 8 nM, 382 nM, 85 nM, 1200 nM and 2 nM, respectively. CM 272 inhibits cell proliferation and promotes apoptosis, inducing IFN stimulated genes and immunogenic cell death. Anti tumour Activity. Product information CAS Number: 1846570 31 7 Molecular Weight:
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