DS-1205b free base 9984A Smiles: CC1=CC=C(C=C1C(O)=O)OC1NC2=CC(=C(Cl)C=C2N=1)C1=CC2C=CN(C)C=2C=C1

Smiles: CC1=CC=C(C=C1C(O)=O)OC1NC2=CC(=C(Cl)C=C2N=1)C1=CC2C=CN(C)C=2C=C1

0 mg/kg DAC in combination with 167 mg/kg Tetrahydrouridine in animals

CCN(CC(O)CS([O-])(=O)=O)C1=CC(=CC=C1)OC

23)17-15-28-13-11-26-8-7-24-4/h5-18H2

CAS Number: 1431698-47-3

DS-1205b free base 9984A Smiles: CC1=CC=C(C=C1C(O)=O)OC1NC2=CC(=C(Cl)C=C2N=1)C1=CC2C=CN(C)C=2C=C1DS 1205b free base is a potent and selective inhibitor of AXL kinase, with an IC50 of 1. 3 nM. DS 1205b free base also inhibits MER, MET, and TRKA, with IC50s of 63, 104, and 407 nM, respectively. DS 1205b free base can inhibit cell migration in vitro and tumor growth in vivo. Product information CAS Number: 1855860 24 0 Molecular Weight: 735. 80 Formula: C41H42FN5O7 Chemical Name: N {4 [2 amino 5 (4 {[(2R) 1,4 dioxan 2 yl]methoxy} 3