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PD173955 - CAS# 260415-63-2 Catalog No.:M11371-2 1993 Sep 1

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Description

1993 Sep 1

In vitro and in vivo activities of LCB01-0371

Epub 2019 Jul 2

also known as BIBN-4096 or BIBN-4096BS is is the first potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor

PubMed PMID: 19338769

PD173955 - CAS# 260415-63-2 Catalog No.:M11371-2 1993 Sep 1PD 173955 is a src tyrosine kinase inhibitor. PD173955 inhibited Bcr Abl dependent cell growth. PD173955 showed cell cycle arrest in G(1). PD173955 has an IC(50) of 1 2 nM in kinase inhibition assays of Bcr Abl, and in cellular growth assays it inhibits Bcr Abl dependent substrate tyrosine phosphorylation. PD173955 inhibited kit ligand dependent c kit autophosphorylation (IC(50) = approximately 25 nM) and kit ligand dependent proliferation of M07e

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