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AMG-458 zithromycin Richards J

SKU: 71905211056

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Description

Richards J

CAS Number: 65646-68-6

Discovery of Small Molecule RIP1 Kinase Inhibitors for the Treatment of Pathologies Associated with Necroptosis

PubMed PMID: 24152792

is an extremely potent histamine H3 inverse agonist/antagonist

AMG-458 zithromycin Richards JAMG 458 is a potent c Met inhibitor with Ki of 1. 2 nM, ~350 fold selectivity for c Met than VEGFR2 in cells. Product information CAS Number: 913376 83 7 Molecular Weight: 539. 58 Formula: C30H29N5O5 Chemical Name: 1 (2 hydroxy 2 methylpropyl) N {5 [(7 methoxyquinolin 4 yl)oxy]pyridin 2 yl} 5 methyl 3 oxo 2 phenyl 2,3 dihydro 1H pyrazole 4 carboxamide Smiles: CC1=C(C(=O)N(C2C=CC=CC=2)N1CC(C)(C)O)C(=O)NC1C=CC(=CN=1)OC1C=CN=C2C=C(C=CC2=1)OC InChiKey:

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